trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide
N,N'-((1R,4R)-CYCLOHEXANE-1,4-DIYL)BIS(2-(4-CHLOROPHENOXY)ACETAMIDE)
CAS: 548470-11-7
Molecular Formula: C22H24Cl2N2O4
trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide - Names and Identifiers
| Name | N,N'-((1R,4R)-CYCLOHEXANE-1,4-DIYL)BIS(2-(4-CHLOROPHENOXY)ACETAMIDE) |
| Synonyms | ISRIB Integrated Stress Response inhibitor N,N'-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide N,N'-((1R,4R)-CYCLOHEXANE-1,4-DIYL)BIS(2-(4-CHLOROPHENOXY)ACETAMIDE) 2-(4-chlorophenoxy)-N-(4-{[(4-chlorophenoxy)acetyl]amino}cyclohexyl)acetami de 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide ISRIB N,N'-((1R,4R)-CYCLOHEXANE-1,4-DIYL)BIS(2-(4-CHLOROPHENOXY)ACETAMIDE) |
| CAS | 548470-11-7 |
trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide - Physico-chemical Properties
| Molecular Formula | C22H24Cl2N2O4 |
| Molar Mass | 451.34 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Melting Point | 270-273°C |
| Boling Point | 719.0±60.0 °C(Predicted) |
| Solubility | DMSO: 1 mg/mL, clear (warmed) |
| Appearance | powder |
| Color | white to beige |
| pKa | 13.63±0.40(Predicted) |
| Storage Condition | 2-8°C |
trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide - Risk and Safety
| Hazard Symbols | N - Dangerous for the environment |
| Risk Codes | 50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 3 |
trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.216 ml | 11.078 ml | 22.156 ml |
| 5 mM | 0.443 ml | 2.216 ml | 4.431 ml |
| 10 mM | 0.222 ml | 1.108 ml | 2.216 ml |
| 5 mM | 0.044 ml | 0.222 ml | 0.443 ml |
Last Update：2024-01-02 23:10:35
trans-N,N′-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)-acetamide - Introduction
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-chroophenoxy) ACETAMIDE), also known as N,N'-dicyclohexyl-1,4-dioxane-2,5-dicarboxamide, the molecular formula C22H36ClNO4 is an organic compound.
Nature:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-chroophenoxy) ACETAMIDE) is a colorless crystalline solid with low solubility. It is a non-volatile solid at room temperature and has good thermal stability.
Use:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-chloroform) ACETAMIDE) is mainly used as a reaction aid and solvent in polymer materials. It can significantly increase the molecular weight of polyurethane and polyamide, improve the mechanical properties and thermal stability of the material. In addition, it can also be used in the fields of dyes, plastics, coatings and adhesives.
Preparation Method:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-CHLOROPHENOXY)ACETAMIDE) can be prepared by 1, 4-Cyclohexanedione and 2-(4-chlorophenoxy) acetamide are reacted under acidic conditions. Heating is required during the reaction, and an appropriate amount of solvent is added to promote the reaction.
Safety Information:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-chroophenoxy) ACETAMIDE) has low toxicity under general operation, however, it is still necessary to follow reasonable laboratory practices. Care should be taken to avoid direct contact with skin, eyes or mucous membranes and to maintain good ventilation. If accidental contact, should immediately rinse with water, if necessary, seek medical attention.
Nature:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-chroophenoxy) ACETAMIDE) is a colorless crystalline solid with low solubility. It is a non-volatile solid at room temperature and has good thermal stability.
Use:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-chloroform) ACETAMIDE) is mainly used as a reaction aid and solvent in polymer materials. It can significantly increase the molecular weight of polyurethane and polyamide, improve the mechanical properties and thermal stability of the material. In addition, it can also be used in the fields of dyes, plastics, coatings and adhesives.
Preparation Method:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-CHLOROPHENOXY)ACETAMIDE) can be prepared by 1, 4-Cyclohexanedione and 2-(4-chlorophenoxy) acetamide are reacted under acidic conditions. Heating is required during the reaction, and an appropriate amount of solvent is added to promote the reaction.
Safety Information:
N,N'-((1R,4R)-CYCLOHEXANE-1,4-diyl) BIS(2-(4-chroophenoxy) ACETAMIDE) has low toxicity under general operation, however, it is still necessary to follow reasonable laboratory practices. Care should be taken to avoid direct contact with skin, eyes or mucous membranes and to maintain good ventilation. If accidental contact, should immediately rinse with water, if necessary, seek medical attention.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: N,N'-((1R,4R)-CYCLOHEXANE-1,4-DIYL)BIS(2-(4-CHLOROPHENOXY)ACETAMIDE) Visit Supplier Webpage Request for quotationCAS: 548470-11-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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